1.终端输入fsl后打开BET

sMRI剥脑壳--基于FSL_BET

输入图像位置,生成图像位置,设置图像密度阈值f(f值越小,切割大脑轮廓设定越大), 选择bet执行算法,点击Go运行

 

2.参数选择(点击Advanced options)

-f <f> fractional intensity threshold (0->1); default=0.5; smaller values give larger brain outline estimates 

下图图灰色的是f=0.2的结果,蓝色是f=0.8的结果,如果初始参数设置后发现脑壳剥多了,将f参数改小,留下较大的大脑区域

sMRI剥脑壳--基于FSL_BET

-g <g> vertical gradient in fractional intensity threshold (-1->1); default=0; positive values give larger brain outline at bottom, smaller at top

如果剥脑壳后下部区域有脖子,额叶顶叶区域不完整,应设为负数,且越小顶部保留越多,底部保留越少

 

-r <r> head radius (mm not voxels); initial surface sphere is set to half of this

如果被试头部不够标准,可以修改大脑的半径以保留全部大脑区域

 

-c < x y z> centre-of-gravity (voxels not mm) of initial mesh surface.

定义大脑中心位置,在mricron中打开原图后手动选定大脑区域的中心坐标,如下图Z值过大,应将矢状面的坐标向左移

sMRI剥脑壳--基于FSL_BET

 

切割算法选择如下,一般使用自定义算法即可,通过调整参数修正剥脑壳

(自定义) run bet2

-R  "robust" brain centre estimation

-S cleanup residual eye and optic nerve voxel

-B reduce image bias, and residual neck voxels

-Z improve the brain extraction if only a few slices are present in the data

-F uses bet2 to determine a brain mask on the basis of the first volume in a 4D data set, and applies this to the whole data set

-A runs both bet2 and betsurf programs in order to get the additional skull and scalp surfaces created by betsurf.

-A2 <T2> This is the same as -A except that a T2 image is also input, to further improve the estimated skull and scalp surfaces.

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