如何使用 gtsummary 包在 tbl_regression 表中添加趋势 p 值测试

Question

我目前正在尝试添加一个具有 p 值评估线性趋势线性回归模型的列。我无法在文档中找到解决方案。有没有人找到解决这个问题的方法？如果有，可以分享给我吗？

我在下面包含了虚拟数据和代码：

 # install dev versions
remotes::install_github("ddsjoberg/gtsummary@mice_nnet")
remotes::install_github("larmarange/broom.helpers")

# load packages
library(gtsummary)
library(nnet)

theme_gtsummary_compact()

# dummy data 
crime <-data.frame(city = sample(as.factor(c(1, 2, 3,4)),13000,replace = TRUE),
                   sex = sample(c("Male", "Female"),13000,replace = TRUE),
                   year = sample(as.numeric(sample(10:70, 13000, replace = TRUE)))
)

# serperate data sets by sex
crime_f <- crime %>%
  filter(sex == "Female")

crime_m <- crime %>%
  filter(sex == "Male")

# build model for females
mod_f <- lm(year ~ city, data = crime_f, na.action=na.exclude) 

# build model for males
mod_m <- lm(year ~ city, data = crime_m, na.action=na.exclude)

# linear trend test between year and city
# females
mod2_f <- lm(year ~ as.numeric(city), data = crime_f, na.action=na.exclude)

# males
mod2_m <- lm(year ~ as.numeric(city), data = crime_m, na.action=na.exclude)

# make regression table from results
# femlaes
tbl_regression(mod_f,
               exponentiate = TRUE) %>%
  modify_header(estimate ~ "**OR**")

# males
tbl_regression(mod_m,
               exponentiate = TRUE) %>%
  modify_header(estimate ~ "**OR**")


# lm model tabulated with gtsummary  
tbl <- tbl_merge(
  tbls = list(mod_f, mod_m),
  tab_spanner = c("**Female**", "**Male**")
)

Answer 1

最简单的方法是建立两个模型（一个常规模型，一个将变量视为连续模型），然后将表合并在一起。下面的例子。

# load packages
library(gtsummary)
theme_gtsummary_compact()

# model cyl as a categorical 
mod1 <- lm(mpg ~ cyl, data = mtcars %>% dplyr::mutate(cyl = factor(cyl)))
# model cyl as continuous (p-trend)
mod2 <- lm(mpg ~ cyl, data = mtcars)

# summarize primary model
tbl1 <- tbl_regression(mod1)
# summarize model with p-trend, and hide the estimate and CI
tbl2 <- tbl_regression(mod2) %>%
  modify_table_header(c(estimate, ci), hide = TRUE) %>%
  modify_header(p.value ~ "**p-trend**")

# merge primary model and p-trend
tbl_merge(list(tbl1, tbl2)) %>%
  # remove spanning header
  modify_spanning_header(everything() ~ NA)