原因：
I just ran into this same issue. It's caused by having your "My Documents" folder mapped to a different drive. The installer and program assume it's located on the C:/ drive and attempt to create or open the workspace there.
就是由于你把“我的文档”的位置修改造成的。但Aptana还以为“我的文档”的位置是在系统的默认路径下。
解决办法：
Create a new shortcut for Aptana (or modify the existing one) and add a -data parameter with the path to your workspace folder (by default under your documents). On my system it is setup like so:
意思是说：
创建一个新的Aptana快捷方式（或修改现有的），在快捷方式的目标后面添加一个workspace路径参数即可。
"D:/Program Files/Aptana Studio 3/AptanaStudio3.exe" -data "D:/Workspaces/Aptana Studio 3"
源自：http://stackoverflow.com/questions/1830528/aptana-studio-wont-load
解决办法二：
找到Aptana Studio 3/configuration路径下，找到config.ini
将其中的
osgi.instance.area.default=@user.home/My Documents/Aptana Studio 3 Workspace
改成
osgi.instance.area.default=@user.home/Documents/Aptana Studio 3 Workspace
即可。